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Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Supercooling enables long-term transplantation survival following 4 days of liver preservation.
Nature Medicine 2014 July
The realization of long-term human organ preservation will have groundbreaking effects on the current practice of transplantation. Herein we present a new technique based on subzero nonfreezing preservation and extracorporeal machine perfusion that allows transplantation of rat livers preserved for up to four days, thereby tripling the viable preservation duration.
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