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Journal Article
Review
No effect of proton pump inhibitors on crying and irritability in infants: systematic review of randomized controlled trials.
Journal of Pediatrics 2015 March
Proton pump inhibitors are increasingly being used to treat infants with crying and/or irritability based on the assumption that these symptoms are attributable to gastroesophageal reflux. However, the data from a systematic review of randomized controlled trials do not support the use of proton pump inhibitors to decrease infant crying and irritability.
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