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The rate and significance of type 1/type 2 serum amyloid A protein gene polymorphisms in patients with ankylosing spondylitis and amyloidosis.

Gozde Yildirim Cetin, Eda Ganiyusufoglu, Dilek Solmaz, Yonca Cagatay, Sibel Yılmaz Oner, Burak Erer, Hasan Sabit Sagliker, Ali Berkant Avci, Servet Akar, Omer Nuri Pamuk, Metin Kılınc, Timucin Kasifoglu, Haner Direskeneli, Ahmet Gul, Mehmet Sayarlioglu
Amyloid : the International Journal of Experimental and Clinical Investigation 2015
A relationship between the presence of amyloidosis and SAA1 genotype has been shown in recent studies of (principally) familial Mediterranean fever patients. We found that the SAA1 rs12218 polymorphism was significantly more prevalent in ankylosing spondylitis patients with amyloidosis.

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