Add like
Add dislike
Add to saved papers

Premedication Methods in Nasal Endoscopy: A Prospective, Randomized, Double-Blind Study.

OBJECTIVES: To identify the optimal pharmacological method of preparing patients for nasal endoscopy.

METHODS: Twenty healthy volunteers were enrolled in this prospective, randomized, double-blind study. Four types of medications were applied in their nostrils with binary combinations of spray bottles on four different days in a random order: placebo (normal saline [NS]+NS), decongestant (NS+oxymetazoline), anesthetic (NS+lidocaine), and decongestant plus anesthetic (oxymetazoline+lidocaine). Rigid nasal endoscopy was performed 10 minutes after spray application. The volunteers evaluated the discomfort caused by each spray application, and nasal pain scores due to the passage of the endoscope. The physicians quantified nasal decongestion using a visual analogue scale. Endoscopy duration as well as pulse and mean blood pressure (MBP) before spray application, 10 minutes after the application, and immediately after endoscopic examination were also recorded.

RESULTS: The discomfort caused by lidocaine was significantly higher than that caused by the other sprays ( P <0.001). The lowest pain score related to endoscopy was obtained for oxymetazoline+lidocaine ( P <0.001). Nasal decongestion was best achieved with NS+oxymetazoline ( P <0.001). Endoscopy duration was the shortest for oxymetazoline+ lidocaine ( P <0.05). Statistically significant MBP changes were only seen with the application of NS+oxymetazoline ( P <0.05). However, neither MBP nor pulse rate change was significant clinically.

CONCLUSION: Application of decongestant and anesthetic sprays together seems to be the best method of pharmacological preparation of patients for nasal endoscopy.

Full text links

We have located links that may give you full text access.
Can't access the paper?
Try logging in through your university/institutional subscription. For a smoother one-click institutional access experience, please use our mobile app.

For the best experience, use the Read mobile app

Mobile app image

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app

All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

By using this service, you agree to our terms of use and privacy policy.

Your Privacy Choices Toggle icon

You can now claim free CME credits for this literature searchClaim now

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app