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JOURNAL ARTICLE
SYSTEMATIC REVIEW
The 2 years' long-term efficacy and safety of peroral endoscopic myotomy for the treatment of achalasia: a systematic review.
Journal of Cardiothoracic Surgery 2019 January 4
AIM: In this retrospective review, we aimed to investigate the long-term efficacy and safety of POEM with follow-up period over 2 years.
MATERIALS AND METHODS: A systematic review related to POEM for achalasia was conducted. A literature search was performed in Pubmed, Medline, Ovid, Cochrane and EBSCO databases on November 2017. The following postoperative outcomes were extracted: Eckardt score, lower esophageal sphincter pressure, complications and clinical success.
RESULTS: The total number of patients was 373. The mean operative time was 66.7 min and the overall rate of complications was 21.2%. The mean follow-up period was 30.0 months. The overall clinical success rate was 92.9% and the rate of gastroesophageal reflux disease was 10.2%. Rate of mortality after POEM was 0.
CONCLUSIONS: Our study demonstrated that POEM is effective and safe for treating achalasia during the long-term followed up over 2 years.
MATERIALS AND METHODS: A systematic review related to POEM for achalasia was conducted. A literature search was performed in Pubmed, Medline, Ovid, Cochrane and EBSCO databases on November 2017. The following postoperative outcomes were extracted: Eckardt score, lower esophageal sphincter pressure, complications and clinical success.
RESULTS: The total number of patients was 373. The mean operative time was 66.7 min and the overall rate of complications was 21.2%. The mean follow-up period was 30.0 months. The overall clinical success rate was 92.9% and the rate of gastroesophageal reflux disease was 10.2%. Rate of mortality after POEM was 0.
CONCLUSIONS: Our study demonstrated that POEM is effective and safe for treating achalasia during the long-term followed up over 2 years.
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