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Updates in IDH-Wildtype Glioblastoma.

Jawad M Melhem, Jay Detsky, Mary Jane Lim-Fat, James R Perry
Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics 2022 October
Glioblastoma is the most aggressive primary brain tumor with a poor prognosis. The 2021 WHO CNS5 classification has further stressed the importance of molecular signatures in diagnosis although therapeutic breakthroughs are still lacking. In this review article, updates on the current and novel therapies in IDH-wildtype GBM will be discussed.

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