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Research Support, U.S. Gov't, P.H.S.
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Malignant transformation rate in oral submucous fibrosis over a 17-year period.

P R Murti, R B Bhonsle, J J Pindborg, D K Daftary, P C Gupta, F S Mehta
Community Dentistry and Oral Epidemiology 1985 December
Sixty-six patients with oral submucous fibrosis were followed-up for a period of 17 yr (median observation 10 yr) in Ernakulam District, Kerala, India. Oral cancer developed in five (7.6%) patients. The malignant transformation rate in the same sample was 4.5% over a 15-yr observation period (median 8 yr). These findings impart a high degree of malignant potential to this condition.

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