JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
RESEARCH SUPPORT, U.S. GOV'T, P.H.S.
Add like
Add dislike
Add to saved papers

Intraductal dysplasia: a premalignant lesion of the prostate.

Human Pathology 1986 January
Foci of cytologic atypia with some of the histologic features of malignancy were identified in ductal and acinar lining epithelia from 100 serially blocked prostates with adenocarcinoma and 100 benign prostates obtained at autopsy. Criteria for diagnosis and grading of severity were established for this lesion, which is referred to as intraductal dysplasia. The histologic features, extent, and severity of intraductal dysplasia were compared between the two groups. Eighty-two prostates with carcinoma and 43 benign prostates contained foci of dysplasia. The severity (grade) and extent of dysplasia were greater in the prostates with carcinoma. Grade 3 dysplasia was found in 33 per cent of the prostates with cancer but in only 4 per cent of the benign prostates. The frequency of multiple, independent invasive carcinomas was high among prostates with multiple foci of dyplasia. It was concluded that dysplasia is probably a direct biologic precursor of prostatic carcinoma and may be the antecedent lesion in the majority of prostatic cancers.

Full text links

We have located links that may give you full text access.
Can't access the paper?
Try logging in through your university/institutional subscription. For a smoother one-click institutional access experience, please use our mobile app.

For the best experience, use the Read mobile app

Mobile app image

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app

All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

By using this service, you agree to our terms of use and privacy policy.

Your Privacy Choices Toggle icon

You can now claim free CME credits for this literature searchClaim now

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app