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JOURNAL ARTICLE
REVIEW
Bacterial meningitis--1982.
American Journal of Medicine 1983 July 29
The etiologic agents in bacterial meningitis vary with time, geography, and patient age. Predominant pathogens are Escherichia coli, group B streptococci, Listeria monocytogenes, Haemophilus influenzae, Neisseria meningitidis, and Streptococcus pneumoniae. Approximately 70 percent of all cases occur in children under the age of five. The case-fatality rate in the United States in 1978 was 13.6 percent, but it is known that underreporting of cases, and therefore of case-fatalities, occurs. Prevention by vaccine appears to be the ultimate solution, but until a vaccine is developed emphasis should be on rapid diagnosis, improved management, and proper choice of antibiotic.
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