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Decrease in serum testosterone concentration during treatment with tetracycline.
Acta Endocrinologica 1983 June
Serum concentrations of testosterone and the binding capacity of sex hormone binding globulin (SHBG) were measured on days 2 days immediately preceding tetracycline treatment, on 3 days of treatment and on 2 days immediately after cessation of treatment. On the treatment days serum mean testosterone concentrations were significantly lower than on the control days (17 +/- 0.9 vs 21 +/- 0.8 nmol/l, P less than 0.01). There were no differences in the SHBG. The 'free testosterone index' behaved like the total testosterone.
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