We have located links that may give you full text access.
CLINICAL TRIAL
COMPARATIVE STUDY
CONTROLLED CLINICAL TRIAL
JOURNAL ARTICLE
The significance of isoechoic prostatic carcinoma.
Journal of Urology 1994 December
The diagnosis of prostatic carcinoma is most commonly made today by transrectal ultrasound guided needle biopsy. Often hypoechoic and peripheral zone lesions are the only areas sampled. Recently, we showed that this approach missed a quarter of the cancers that would be detected by a systematic biopsy technique. We term these missed cancers isoechoic carcinomas. We reviewed 1,549 systematic sextant prostate needle biopsies, of which 417 cancers were detected and subdivided into hypoechoic cancers (cancers detected on biopsy of a hypoechoic sector and isoechoic cancers (cancers found only in normal [isoechoic] peripheral zone). We noted in men with only isoechoic cancers that fewer biopsy cores per prostate revealed cancer (mean 1.6 versus 3.0, p < 0.0001) and that these men had lower serum prostate specific antigen levels (mean 14.4 versus 43.7, p < 0.001). The Gleason scores for the isoechoic and hypoechoic cancers were indistinguishable. The pathological staging of hypoechoic and isoechoic cancers was also similar. This study suggests that while isoechoic cancers are generally smaller than hypoechoic cancers, they do not represent low grade clinically insignificant carcinomas. A systematic approach to performing prostate biopsy is recommended.
Full text links
Related Resources
Trending Papers
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical Research in Cardiology : Official Journal of the German Cardiac Society 2024 April 12
Proximal versus distal diuretics in congestive heart failure.Nephrology, Dialysis, Transplantation 2024 Februrary 30
Efficacy and safety of pharmacotherapy in chronic insomnia: A review of clinical guidelines and case reports.Mental Health Clinician 2023 October
World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.American Journal of Hematology 2024 March 30
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app