We have located links that may give you full text access.
Aggressive bone tumorous lesion in infancy: osteofibrous dysplasia of the tibia and fibula.
Journal of Pediatric Orthopedics 1993 September
The clinical experiences of 10 patients with osteofibrous dysplasia were reviewed. Mean age of the patients was 7.3 years; all had an intracortical, eccentric lesion in the anterior aspect of the shaft of the tibia. Seven of the patients underwent either an excision or an en bloc resection; the lesion recurred in four of the seven, and one showed pseudarthrosis. Surgical outcomes were unsatisfactory, especially in the younger patients. In contrast, the remaining three patients who did not undergo surgery showed satisfactory results. Nonsurgical treatment is generally recommended except in cases in which impending deformities seem certain. Osteofibrous dysplasia was characterized histologically by osteoid rimmed by osteoblasts, sinusoid surrounding osteoid, many osteoclasts in the sinusoid, and fibrous stroma. Ultrastructurally, stroma cells revealed the characteristics of preosteoblasts. Osteogenic potentiality was well-documented. This tumorous condition is likely attributed to dysremodelling, in which osteoclastosis is dominant to osteogenesis. Abnormal blood circulation in the periosteum is the likely pathogenesis of osteofibrous dysplasia.
Full text links
Related Resources
Trending Papers
Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of Personalized Medicine 2024 Februrary 4
Molecular Targets of Novel Therapeutics for Diabetic Kidney Disease: A New Era of Nephroprotection.International Journal of Molecular Sciences 2024 April 4
Perioperative echocardiographic strain analysis: what anesthesiologists should know.Canadian Journal of Anaesthesia 2024 April 11
The 'Ten Commandments' for the 2023 European Society of Cardiology guidelines for the management of endocarditis.European Heart Journal 2024 April 18
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app