Multiple giant disseminated pyogenic granuloma in three patients burned by boiling milk.

BACKGROUND: Pyogenic granuloma is a common benign skin tumor. The multiple disseminated form of the disease is relatively rare.

METHODS: We examined three patients who developed giant pyogenic granuloma after burns from boiling milk. The patients were a 1.5-year-old boy, a 5-year-old girl, and a 35-year-old woman, All three patients had second-degree burns over their face and trunk.

RESULTS: In these patients, pyogenic granuloma had developed over the previously burned areas 2-3 weeks after exposure. The general condition of the patients remained good and all lesions involuted spontaneously. In a 6-month follow-up period no relapse of the lesions was seen.

CONCLUSIONS: The cause for development of multiple giant pyogenic granulomas after burns from milk remains unknown, but milk proteins or other components of milk, microorganisms, or the burn itself may be causative factors.