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Complete remission of multicentric reticulohistiocytosis with combination therapy of steroid, cyclophosphamide, and low-dose pulse methotrexate. Case report, review of the literature, and proposal for treatment.
Arthritis and Rheumatism 1996 January
We describe a patient with multicentric reticulohistiocytosis in whom complete remission was achieved by sequential combination therapy with steroid, methotrexate, and cyclophosphamide. We reviewed all cases of complete or near-complete remissions of multicentric reticulohistiocytosis reported in the English-language literature and propose a new drug regimen for this rare but potentially disabling disease.
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