IgA deficiency and psoriasis: relevance of IgA in the pathogenesis of psoriasis.

P C van de Kerkhof, P M Steijlen

Dermatology : International Journal for Clinical and Investigative Dermatology 1995

A psoriatic patient with absolute deficiency of IgA is reported. The manifestations of psoriasis appeared at the age of 6 months and proved to be resistant to various treatments. The present case report and the data available in the literature on IgA and psoriasis all converge on the hypothesis that IgA is a systemic factor which belongs to the 'off switches' of the psoriatic process.

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