We have located links that may give you full text access.
CASE REPORTS
JOURNAL ARTICLE
REVIEW
The surgical complications of Ehlers-Danlos syndrome.
American Surgeon 1996 October
Between January 1975 and July 1995, 44 gastrointestinal and 45 vascular complications of Ehlers-Danlos syndrome type IV (EDS-IV) were reported in the literature. This included 41 colon perforations, 2 paraesophageal hernias, 22 spontaneous hemorrhages, 17 aneurysms, and 5 arterial dissections. Twenty-seven colonic perforations were treated with resection and diversion, 11 with total abdominal colectomy (TAC), and 3 with primary colon repair. Reperforation occurred in 15 resection/diversion patients versus none treated with TAC (P < 0.05). Seven patients (23.3%) died from their gastrointestinal complications. Eleven vascular complications were treated with nonoperative management, eight with vessel ligation, 20 with arterial reconstruction, and two with therapeutic angiography. Eighteen patients underwent angiography, with three (22%) major complications and one death (5.6%). Twelve (30%) patients died from vascular complications of EDS-IV, seven of whom had been treated with arterial reconstruction (P < 0.05). This review supports treating colon perforations in EDS-IV patients with TAC and end ileostomy to avoid a reperforation or an anastamotic leak. EDS-IV patients with vascular complications should be treated with nonoperative therapy and noninvasive imaging techniques when possible. Operative intervention, when required, should focus on simple vessel ligation rather than reconstruction.
Full text links
Related Resources
Trending Papers
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical Research in Cardiology : Official Journal of the German Cardiac Society 2024 April 12
Proximal versus distal diuretics in congestive heart failure.Nephrology, Dialysis, Transplantation 2024 Februrary 30
World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.American Journal of Hematology 2024 March 30
Efficacy and safety of pharmacotherapy in chronic insomnia: A review of clinical guidelines and case reports.Mental Health Clinician 2023 October
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app