Indocyanine green angiography of acute multifocal posterior placoid pigment epitheliopathy.

PURPOSE: To understand the pathophysiology of acute multifocal posterior placoid pigment epitheliopathy (AMPPPE).

METHODS: Indocyanine green (ICG) angiography was used for three patients, four eyes with acute AMPPPE and four eyes with healed AMPPPE.

RESULTS: The angiographic photographs demonstrated widespread choroidal hypofluorescence of the active and healed lesions.

CONCLUSIONS: Although the pathogenesis and histopathology of AMPPPE are unknown, the literature suggests that AMPPPE may represent an inflammatory reaction, possibly a delayed-type hypersensitivity reaction. The ICG choroidal hypofluorescence in AMPPPE is probably due to partial choroidal vascular occlusion secondary to occlusive vasculitis.