We have located links that may give you full text access.
Menstrual cycle and age: influence on parenchymal contrast medium enhancement in MR imaging of the breast.
Radiology 1997 April
PURPOSE: To evaluate the influence of menstrual cycle and age on parenchymal contrast medium enhancement in magnetic resonance (MR) imaging of the breast.
MATERIALS AND METHODS: Dynamic gadolinium-enhanced fast low-angle shot, three-dimensional breast MR imaging was performed with high temporal and spatial resolution (eight measurements in 10 minutes). Menstrual cycle evaluations and age-influence studies were performed in 44 patients aged 27-55 years with a regular cycle (mean age, 41.5 years) and in 103 patients aged 15-79 years (mean age, 49.3 years), respectively. A region of interest was placed in each quadrant of the breast for evaluation of parenchymal enhancement. Quadrants with complete involution or lesions and patients who received hormonal therapy were excluded [corrected]. Analysis of variance was performed.
RESULTS: Parenchymal contrast medium enhancement in cycle days 7-20 (geometric mean enhancement at minutes 1-10 = 0.12-0.47) was significantly lower than that in cycle days 21-6 (geometric mean, 0.17-0.98; P < or = .001). Contrast medium enhancement in patients aged 35-50 years (mean enhancement, 0.17-0.75) was significantly higher than that in patients aged younger than 35 years or older than 50 years (mean enhancement, 0.12-0.40; P < .01).
CONCLUSION: Patients showed statistically significantly lower parenchymal enhancement in menstrual cycle days 7-20 than in days 21-6. Patients aged 35-50 years yielded higher parenchymal enhancement than did younger patients and older patients.
MATERIALS AND METHODS: Dynamic gadolinium-enhanced fast low-angle shot, three-dimensional breast MR imaging was performed with high temporal and spatial resolution (eight measurements in 10 minutes). Menstrual cycle evaluations and age-influence studies were performed in 44 patients aged 27-55 years with a regular cycle (mean age, 41.5 years) and in 103 patients aged 15-79 years (mean age, 49.3 years), respectively. A region of interest was placed in each quadrant of the breast for evaluation of parenchymal enhancement. Quadrants with complete involution or lesions and patients who received hormonal therapy were excluded [corrected]. Analysis of variance was performed.
RESULTS: Parenchymal contrast medium enhancement in cycle days 7-20 (geometric mean enhancement at minutes 1-10 = 0.12-0.47) was significantly lower than that in cycle days 21-6 (geometric mean, 0.17-0.98; P < or = .001). Contrast medium enhancement in patients aged 35-50 years (mean enhancement, 0.17-0.75) was significantly higher than that in patients aged younger than 35 years or older than 50 years (mean enhancement, 0.12-0.40; P < .01).
CONCLUSION: Patients showed statistically significantly lower parenchymal enhancement in menstrual cycle days 7-20 than in days 21-6. Patients aged 35-50 years yielded higher parenchymal enhancement than did younger patients and older patients.
Full text links
Related Resources
Trending Papers
Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of Personalized Medicine 2024 Februrary 4
Molecular Targets of Novel Therapeutics for Diabetic Kidney Disease: A New Era of Nephroprotection.International Journal of Molecular Sciences 2024 April 4
Perioperative echocardiographic strain analysis: what anesthesiologists should know.Canadian Journal of Anaesthesia 2024 April 11
The 'Ten Commandments' for the 2023 European Society of Cardiology guidelines for the management of endocarditis.European Heart Journal 2024 April 18
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app