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CASE REPORTS
JOURNAL ARTICLE
Recurrence of medulloblastoma: violation of Collins' law after two decades.
Surgical Neurology 1997 June
BACKGROUND: Medulloblastoma is a common tumor of childhood arising in the posterior fossa. The concept of a child with an embryonal tumor surviving the age of diagnosis plus 9 months as the period of risk for recurrence (Collins' Law) has been applied to medulloblastomas. This raises the question of "when should follow-up stop for a patient with this type of tumor?"
METHODS: We present a case report of a patient with the longest documented exception to Collins' Law for medulloblastoma.
RESULTS: The longest documented exception to Collins' Law, a medulloblastoma recurring 20 years and 8 months after the period of risk for recurrence is presented. Both the site of recurrence and the histopathology were identical to the original tumor.
CONCLUSION: We present the longest documented exception to Collins' Law, to emphasize that even after decades the term "cure" should only be used cautiously.
METHODS: We present a case report of a patient with the longest documented exception to Collins' Law for medulloblastoma.
RESULTS: The longest documented exception to Collins' Law, a medulloblastoma recurring 20 years and 8 months after the period of risk for recurrence is presented. Both the site of recurrence and the histopathology were identical to the original tumor.
CONCLUSION: We present the longest documented exception to Collins' Law, to emphasize that even after decades the term "cure" should only be used cautiously.
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