We have located links that may give you full text access.
Role of cellular proliferation and apoptosis in the growth of xanthogranulomas.
American Journal of Dermatopathology 1998 Februrary
We examined a total of 13 xanthogranulomas in order to examine the mechanism by which these lesions grow. Six xanthogranulomas from children < 2 years of age were compared with lesions from seven patients > 10 years of age. All lesions were stained with antibodies directed against Ki-67 and bcl-2 protein. There were no significant differences between the two groups. There was a slight trend toward higher rates of proliferating histiocytes within lesions from children (p < 0.18). It is unclear from our data whether this higher rate is correlated more with the age of the patient or with the duration of the lesion. Inhibition of cellular apoptosis, as demonstrated by expression of bcl-2, appears to play a minor role in the growth of xanthogranulomas in either children or adults. Xanthogranulomas appear to be tumors that grow by proliferation of "histiocytes," independent of the age of onset.
Full text links
Related Resources
Trending Papers
Proximal versus distal diuretics in congestive heart failure.Nephrology, Dialysis, Transplantation 2024 Februrary 30
World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.American Journal of Hematology 2024 March 30
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical Research in Cardiology : Official Journal of the German Cardiac Society 2024 April 12
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app