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Case Reports
Journal Article
Amitriptyline-induced erythema annulare centrifugum.
Cutis; Cutaneous Medicine for the Practitioner 1999 January
A case of amitriptyline-induced superficial erythema annulare centrifugum (EAC) is reported. Its singular characteristics are prominent epidermal manifestations, with clinical and histologic vesiculation, associated with vacuolar degeneration at the dermoepidermal junction; numerous arciform lesions, accompanied by diffuse erythema on rechallenge; quick change, more rapid than that usually described for EAC; and a short course, in contrast with the usual chronic evolution of EAC. To our knowledge, this is the first reported case of EAC associated with amitriptyline intake.
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